Solutions by everydaycalculation.com
1st number: 1/50, 2nd number: 1 1/3
150 - 43 is -197150.
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Related: 2/50-4/3 1/50-8/3 1/50-4/6 3/50-4/3 1/50-12/3 1/50-4/9 5/50-4/3 1/50-20/3 1/50-4/15 7/50-4/3 1/50-28/3 1/50-4/21
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