Solutions by everydaycalculation.com
1st number: 1/6, 2nd number: 1 4/12
16 - 1612 is -76.
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Related: 2/6-16/12 1/6-32/12 1/12-16/12 1/6-16/24 3/6-16/12 1/6-48/12 1/18-16/12 1/6-16/36 5/6-16/12 1/6-80/12 1/30-16/12 1/6-16/60 7/6-16/12 1/42-16/12 1/6-16/84
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