Solutions by everydaycalculation.com
1st number: 1/6, 2nd number: 4 1/6
16 - 256 is -41.
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Related: 2/6-25/6 1/6-50/6 1/12-25/6 1/6-25/12 3/6-25/6 1/6-75/6 1/18-25/6 1/6-25/18 5/6-25/6 1/30-25/6 1/6-25/30 7/6-25/6 1/42-25/6 1/6-25/42
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