Solutions by everydaycalculation.com
1st number: 1/6, 2nd number: 1 1/3
16 - 43 is -76.
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Related: 2/6-4/3 1/6-8/3 1/12-4/3 1/6-4/6 3/6-4/3 1/6-12/3 1/18-4/3 1/6-4/9 5/6-4/3 1/6-20/3 1/30-4/3 1/6-4/15 7/6-4/3 1/6-28/3 1/42-4/3 1/6-4/21
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