Solutions by everydaycalculation.com
1st number: 1/6, 2nd number: 10 4/6
16 - 646 is -212.
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Related: 2/6-64/6 1/12-64/6 1/6-64/12 3/6-64/6 1/18-64/6 1/6-64/18 5/6-64/6 1/30-64/6 1/6-64/30 7/6-64/6 1/42-64/6 1/6-64/42
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