Solutions by everydaycalculation.com
221 - 49 is -2263.
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Related: 4/21-4/9 2/21-8/9 2/42-4/9 2/21-4/18 6/21-4/9 2/21-12/9 2/63-4/9 2/21-4/27 10/21-4/9 2/21-20/9 2/21-4/45 14/21-4/9 2/21-28/9 2/21-4/63
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