Solutions by everydaycalculation.com
1st number: 8 0/3, 2nd number: 1/6
243 - 16 is 476.
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Related: 48/3-1/6 24/3-2/6 24/6-1/6 24/3-1/12 72/3-1/6 24/3-3/6 24/9-1/6 24/3-1/18 24/3-5/6 24/15-1/6 24/3-1/30 24/3-7/6 24/21-1/6 24/3-1/42
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