Solutions by everydaycalculation.com
1st number: 1 1/3, 2nd number: 2 3/21
43 - 4521 is -1721.
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Related: 8/3-45/21 4/3-90/21 4/6-45/21 4/3-45/42 12/3-45/21 4/9-45/21 4/3-45/63 20/3-45/21 4/15-45/21 28/3-45/21 4/21-45/21
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