Solutions by everydaycalculation.com
1st number: 1/6, 2nd number: 1 4/21
16 - 2521 is -4342.
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Related: 2/6-25/21 1/6-50/21 1/12-25/21 1/6-25/42 3/6-25/21 1/6-75/21 1/18-25/21 1/6-25/63 5/6-25/21 1/30-25/21 7/6-25/21 1/42-25/21
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