Solutions by everydaycalculation.com
1st number: 1/6, 2nd number: 2 13/16
16 - 4516 is -12748.
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Related: 2/6-45/16 1/6-90/16 1/12-45/16 1/6-45/32 3/6-45/16 1/18-45/16 1/6-45/48 5/6-45/16 1/30-45/16 1/6-45/80 7/6-45/16 1/42-45/16
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