Solutions by everydaycalculation.com
1st number: 8 0/3, 2nd number: 4/21
243 - 421 is 16421.
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Related: 48/3-4/21 24/3-8/21 24/6-4/21 24/3-4/42 72/3-4/21 24/3-12/21 24/9-4/21 24/3-4/63 24/3-20/21 24/15-4/21 24/3-28/21 24/21-4/21
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