Solutions by everydaycalculation.com
1st number: 4/21, 2nd number: 2 3/21
421 - 4521 is -4121.
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Related: 8/21-45/21 4/21-90/21 4/42-45/21 4/21-45/42 12/21-45/21 4/63-45/21 4/21-45/63 20/21-45/21 28/21-45/21
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