Solutions by everydaycalculation.com
1st number: 4/6, 2nd number: 5 5/6
46 - 356 is -316.
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Related: 8/6-35/6 4/6-70/6 4/12-35/6 4/6-35/12 12/6-35/6 4/18-35/6 4/6-35/18 20/6-35/6 4/30-35/6 4/6-35/30 28/6-35/6 4/42-35/6 4/6-35/42
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