Solutions by everydaycalculation.com
1st number: 2 1/2, 2nd number: 2 4/6
52 - 166 is -16.
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Related: 10/2-16/6 5/2-32/6 5/4-16/6 5/2-16/12 15/2-16/6 5/2-48/6 5/6-16/6 5/2-16/18 25/2-16/6 5/2-80/6 5/10-16/6 5/2-16/30 35/2-16/6 5/14-16/6 5/2-16/42
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